See the Unseen, Slice By Slice
See the Unseen, Slice By Slice
See the Unseen, Slice By Slice
A cutting Edge Approach to Volume Electron Microscopy
A cutting Edge Approach to Volume Electron Microscopy
A cutting Edge Approach to Volume Electron Microscopy





Over 30+ Systems Installed Globally
A Microtome that Transforms Any SEM to a Volume SEM
We design, develop and manufacture the revolutionising serial block-face imaging tool - the katana microtome
JEOL
HITACHI
TESCAN
ThermoFisher
CIQTEK
ZEISS
Universal compatibility
Seamlessly integrates with any SEM that has a stage-to-pole piece distance greater than 56 mm. That is 99% of all contemporary FEG SEMs. Official integration with TESCAN and JEOL SEMs.
Plug and play
A simple installation process that takes mere minutes, swiftly preparing your SEM for volume EM imaging.




Precision and stability
Engineered to achieve maximum stiffness alongside nanometre resolution, reliable for extensive imaging periods.
Now available with Precision Charge Neutralisation
Eliminates charging artifacts by delivering a highly targeted ionised gas
See How katana microtome Slices into the 3rd Dimension
Answering Complex Research Questions with High-Resolution Volumetric Imaging
Flatworm Macrostomum Lignano
Macrostomum lignano, a free-living flatworm, presents a valuable model organism in biological research. Its regenerative capabilities and transparent body make it an interesting subject in fields like stem cell biology, aging, and sexual reproduction. Detailed knowledge of its internal morphology is therefore key to gain insights into its biological processes. katana microtome enables the acquisition of the 3D architecture of M.lignano at nanometre resolution, allowing the reconstruction of some cell structures such as cillia, rhabdites, ultrarhabdites and internal vesicles. One significant application was to visualise the intricate network of stem cells in M. lignano, crucial for understanding their remarkable regenerative abilities. This has also helped reveal the unique structural features of the reproductive organs and the interaction of these organs with the surrounding tissues.
Tobacco Seedlings
Tobacco (Nicotiana tabacum) seedlings offer a crucial stage for studying plant development and responses to environmental conditions. Understanding the cellular and subcellular events during seedling development can have significant implications for crop management and genetic engineering efforts. katana microtome is used to visualise the 3D architecture of cell walls and chloroplasts in tobacco seedlings. These structural details can help understand how cell walls expand during plant growth, and the distribution of chloroplasts and their role in seedling development.
Dentin Tubule Occlusion
Sensitive teeth, often caused by exposed dentin tubules, can create significant discomfort for individuals. Various sensitive toothpastes on the market aim to alleviate this issue through a process known as dentin tubule occlusion. A detailed study of this process is crucial to optimising the formulation of these toothpastes. Using katana microtome can visualise the penetration of occlusion agents, usually composed of nanoparticles such as hydroxyapatite or strontium acetate, into dentin tubules. These images reveal how these agents interact with the tubules, their deposition patterns, and ultimately, their effectiveness in tubule occlusion. By comparing pre-treatment and post-treatment images, the occlusion efficacy of various toothpaste formulations can be quantitatively assessed.
Flatworm Macrostomum Lignano
Macrostomum lignano, a free-living flatworm, presents a valuable model organism in biological research. Its regenerative capabilities and transparent body make it an interesting subject in fields like stem cell biology, aging, and sexual reproduction. Detailed knowledge of its internal morphology is therefore key to gain insights into its biological processes. katana microtome enables the acquisition of the 3D architecture of M.lignano at nanometre resolution, allowing the reconstruction of some cell structures such as cillia, rhabdites, ultrarhabdites and internal vesicles. One significant application was to visualise the intricate network of stem cells in M. lignano, crucial for understanding their remarkable regenerative abilities. This has also helped reveal the unique structural features of the reproductive organs and the interaction of these organs with the surrounding tissues.
Tobacco Seedlings
Tobacco (Nicotiana tabacum) seedlings offer a crucial stage for studying plant development and responses to environmental conditions. Understanding the cellular and subcellular events during seedling development can have significant implications for crop management and genetic engineering efforts. katana microtome is used to visualise the 3D architecture of cell walls and chloroplasts in tobacco seedlings. These structural details can help understand how cell walls expand during plant growth, and the distribution of chloroplasts and their role in seedling development.
Dentin Tubule Occlusion
Sensitive teeth, often caused by exposed dentin tubules, can create significant discomfort for individuals. Various sensitive toothpastes on the market aim to alleviate this issue through a process known as dentin tubule occlusion. A detailed study of this process is crucial to optimising the formulation of these toothpastes. Using katana microtome can visualise the penetration of occlusion agents, usually composed of nanoparticles such as hydroxyapatite or strontium acetate, into dentin tubules. These images reveal how these agents interact with the tubules, their deposition patterns, and ultimately, their effectiveness in tubule occlusion. By comparing pre-treatment and post-treatment images, the occlusion efficacy of various toothpaste formulations can be quantitatively assessed.
Flatworm Macrostomum Lignano
Macrostomum lignano, a free-living flatworm, presents a valuable model organism in biological research. Its regenerative capabilities and transparent body make it an interesting subject in fields like stem cell biology, aging, and sexual reproduction. Detailed knowledge of its internal morphology is therefore key to gain insights into its biological processes. katana microtome enables the acquisition of the 3D architecture of M.lignano at nanometre resolution, allowing the reconstruction of some cell structures such as cillia, rhabdites, ultrarhabdites and internal vesicles. One significant application was to visualise the intricate network of stem cells in M. lignano, crucial for understanding their remarkable regenerative abilities. This has also helped reveal the unique structural features of the reproductive organs and the interaction of these organs with the surrounding tissues.
Tobacco Seedlings
Tobacco (Nicotiana tabacum) seedlings offer a crucial stage for studying plant development and responses to environmental conditions. Understanding the cellular and subcellular events during seedling development can have significant implications for crop management and genetic engineering efforts. katana microtome is used to visualise the 3D architecture of cell walls and chloroplasts in tobacco seedlings. These structural details can help understand how cell walls expand during plant growth, and the distribution of chloroplasts and their role in seedling development.
Dentin Tubule Occlusion
Sensitive teeth, often caused by exposed dentin tubules, can create significant discomfort for individuals. Various sensitive toothpastes on the market aim to alleviate this issue through a process known as dentin tubule occlusion. A detailed study of this process is crucial to optimising the formulation of these toothpastes. Using katana microtome can visualise the penetration of occlusion agents, usually composed of nanoparticles such as hydroxyapatite or strontium acetate, into dentin tubules. These images reveal how these agents interact with the tubules, their deposition patterns, and ultimately, their effectiveness in tubule occlusion. By comparing pre-treatment and post-treatment images, the occlusion efficacy of various toothpaste formulations can be quantitatively assessed.
Flatworm Macrostomum Lignano
Macrostomum lignano, a free-living flatworm, presents a valuable model organism in biological research. Its regenerative capabilities and transparent body make it an interesting subject in fields like stem cell biology, aging, and sexual reproduction. Detailed knowledge of its internal morphology is therefore key to gain insights into its biological processes. katana microtome enables the acquisition of the 3D architecture of M.lignano at nanometre resolution, allowing the reconstruction of some cell structures such as cillia, rhabdites, ultrarhabdites and internal vesicles. One significant application was to visualise the intricate network of stem cells in M. lignano, crucial for understanding their remarkable regenerative abilities. This has also helped reveal the unique structural features of the reproductive organs and the interaction of these organs with the surrounding tissues.
Tobacco Seedlings
Tobacco (Nicotiana tabacum) seedlings offer a crucial stage for studying plant development and responses to environmental conditions. Understanding the cellular and subcellular events during seedling development can have significant implications for crop management and genetic engineering efforts. katana microtome is used to visualise the 3D architecture of cell walls and chloroplasts in tobacco seedlings. These structural details can help understand how cell walls expand during plant growth, and the distribution of chloroplasts and their role in seedling development.
Dentin Tubule Occlusion
Sensitive teeth, often caused by exposed dentin tubules, can create significant discomfort for individuals. Various sensitive toothpastes on the market aim to alleviate this issue through a process known as dentin tubule occlusion. A detailed study of this process is crucial to optimising the formulation of these toothpastes. Using katana microtome can visualise the penetration of occlusion agents, usually composed of nanoparticles such as hydroxyapatite or strontium acetate, into dentin tubules. These images reveal how these agents interact with the tubules, their deposition patterns, and ultimately, their effectiveness in tubule occlusion. By comparing pre-treatment and post-treatment images, the occlusion efficacy of various toothpaste formulations can be quantitatively assessed.
Flatworm Macrostomum Lignano
Macrostomum lignano, a free-living flatworm, presents a valuable model organism in biological research. Its regenerative capabilities and transparent body make it an interesting subject in fields like stem cell biology, aging, and sexual reproduction. Detailed knowledge of its internal morphology is therefore key to gain insights into its biological processes. katana microtome enables the acquisition of the 3D architecture of M.lignano at nanometre resolution, allowing the reconstruction of some cell structures such as cillia, rhabdites, ultrarhabdites and internal vesicles. One significant application was to visualise the intricate network of stem cells in M. lignano, crucial for understanding their remarkable regenerative abilities. This has also helped reveal the unique structural features of the reproductive organs and the interaction of these organs with the surrounding tissues.
Flatworm Macrostomum Lignano
Macrostomum lignano, a free-living flatworm, presents a valuable model organism in biological research. Its regenerative capabilities and transparent body make it an interesting subject in fields like stem cell biology, aging, and sexual reproduction. Detailed knowledge of its internal morphology is therefore key to gain insights into its biological processes. katana microtome enables the acquisition of the 3D architecture of M.lignano at nanometre resolution, allowing the reconstruction of some cell structures such as cillia, rhabdites, ultrarhabdites and internal vesicles. One significant application was to visualise the intricate network of stem cells in M. lignano, crucial for understanding their remarkable regenerative abilities. This has also helped reveal the unique structural features of the reproductive organs and the interaction of these organs with the surrounding tissues.
Tobacco Seedlings
Tobacco (Nicotiana tabacum) seedlings offer a crucial stage for studying plant development and responses to environmental conditions. Understanding the cellular and subcellular events during seedling development can have significant implications for crop management and genetic engineering efforts. katana microtome is used to visualise the 3D architecture of cell walls and chloroplasts in tobacco seedlings. These structural details can help understand how cell walls expand during plant growth, and the distribution of chloroplasts and their role in seedling development.
Tobacco Seedlings
Tobacco (Nicotiana tabacum) seedlings offer a crucial stage for studying plant development and responses to environmental conditions. Understanding the cellular and subcellular events during seedling development can have significant implications for crop management and genetic engineering efforts. katana microtome is used to visualise the 3D architecture of cell walls and chloroplasts in tobacco seedlings. These structural details can help understand how cell walls expand during plant growth, and the distribution of chloroplasts and their role in seedling development.
Dentin Tubule Occlusion
Sensitive teeth, often caused by exposed dentin tubules, can create significant discomfort for individuals. Various sensitive toothpastes on the market aim to alleviate this issue through a process known as dentin tubule occlusion. A detailed study of this process is crucial to optimising the formulation of these toothpastes. Using katana microtome can visualise the penetration of occlusion agents, usually composed of nanoparticles such as hydroxyapatite or strontium acetate, into dentin tubules. These images reveal how these agents interact with the tubules, their deposition patterns, and ultimately, their effectiveness in tubule occlusion. By comparing pre-treatment and post-treatment images, the occlusion efficacy of various toothpaste formulations can be quantitatively assessed.
Dentin Tubule Occlusion
Sensitive teeth, often caused by exposed dentin tubules, can create significant discomfort for individuals. Various sensitive toothpastes on the market aim to alleviate this issue through a process known as dentin tubule occlusion. A detailed study of this process is crucial to optimising the formulation of these toothpastes. Using katana microtome can visualise the penetration of occlusion agents, usually composed of nanoparticles such as hydroxyapatite or strontium acetate, into dentin tubules. These images reveal how these agents interact with the tubules, their deposition patterns, and ultimately, their effectiveness in tubule occlusion. By comparing pre-treatment and post-treatment images, the occlusion efficacy of various toothpaste formulations can be quantitatively assessed.
Explore Datasets Produced by katana microtome
More SBF-SEM data on WEBKNOSSOS

Imaged on JEOL IT700. Sample courtesy of Dr Isabelle Bonne, National University of Singapore

Imaged on JEOL IT700. Sample courtesy of Dr Isabelle Bonne, National University of Singapore

Imaged on JEOL IT700. Sample courtesy of Dr Isabelle Bonne, National University of Singapore

Imaged on Zeiss Sigma VP. Sample courtesy of Dr Christel Genoud, University of Lausanne

Imaged on Zeiss Sigma VP. Sample courtesy of Dr Christel Genoud, University of Lausanne

Imaged on Zeiss Sigma VP. Sample courtesy of Dr Christel Genoud, University of Lausanne

Imaged on a TESCAN Clara. Sample courtey of Dr Peter Ladurner, University of Innsbruck.

Imaged on a TESCAN Clara. Sample courtey of Dr Peter Ladurner, University of Innsbruck.

Imaged on a TESCAN Clara. Sample courtey of Dr Peter Ladurner, University of Innsbruck.

Imaged on a Zeiss Sigma VP. Sample courtesy of Alan Kuzirian, Marine Biology Laboratory.

Imaged on a Zeiss Sigma VP. Sample courtesy of Alan Kuzirian, Marine Biology Laboratory.

Imaged on a Zeiss Sigma VP. Sample courtesy of Alan Kuzirian, Marine Biology Laboratory.

Imaged on a Zeiss Sigma VP. Sample courtesy of Alan Kuzirian, Marine Biology Laboratory.

Imaged on a Zeiss Sigma VP. Sample courtesy of Alan Kuzirian, Marine Biology Laboratory.

Imaged on a Zeiss Sigma VP. Sample courtesy of Alan Kuzirian, Marine Biology Laboratory.

Imaged on a Hitachi SU7000. Sample courtesy of Dr Ilya Belevich, University of Helsinki

Imaged on a Hitachi SU7000. Sample courtesy of Dr Ilya Belevich, University of Helsinki

Imaged on a Hitachi SU7000. Sample courtesy of Dr Ilya Belevich, University of Helsinki
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