See the Unseen, Slice By Slice

See the Unseen, Slice By Slice

See the Unseen, Slice By Slice

A cutting Edge Approach to Volume Electron Microscopy

A cutting Edge Approach to Volume Electron Microscopy

A cutting Edge Approach to Volume Electron Microscopy

Over 30+ Systems Installed Globally

A Microtome that Transforms Any SEM to a Volume SEM

We design, develop and manufacture the revolutionising serial block-face imaging tool - the katana microtome

  • JEOL

  • HITACHI

  • TESCAN

  • ThermoFisher

  • CIQTEK

  • ZEISS

Universal compatibility

Seamlessly integrates with any SEM that has a stage-to-pole piece distance greater than 56 mm. That is 99% of all contemporary FEG SEMs. Official integration with TESCAN and JEOL SEMs.

Plug and play

A simple installation process that takes mere minutes, swiftly preparing your SEM for volume EM imaging.

Precision and stability

Engineered to achieve maximum stiffness alongside nanometre resolution, reliable for extensive imaging periods.

Now available with Precision Charge Neutralisation

Eliminates charging artifacts by delivering a highly targeted ionised gas

See How katana microtome Slices into the 3rd Dimension

Answering Complex Research Questions with High-Resolution Volumetric Imaging

Flatworm Macrostomum Lignano

Macrostomum lignano, a free-living flatworm, presents a valuable model organism in biological research. Its regenerative capabilities and transparent body make it an interesting subject in fields like stem cell biology, aging, and sexual reproduction. Detailed knowledge of its internal morphology is therefore key to gain insights into its biological processes. katana microtome enables the acquisition of the 3D architecture of M.lignano at nanometre resolution, allowing the reconstruction of some cell structures such as cillia, rhabdites, ultrarhabdites and internal vesicles. One significant application was to visualise the intricate network of stem cells in M. lignano, crucial for understanding their remarkable regenerative abilities. This has also helped reveal the unique structural features of the reproductive organs and the interaction of these organs with the surrounding tissues.

Flatworm Macrostomum Lignano

Macrostomum lignano, a free-living flatworm, presents a valuable model organism in biological research. Its regenerative capabilities and transparent body make it an interesting subject in fields like stem cell biology, aging, and sexual reproduction. Detailed knowledge of its internal morphology is therefore key to gain insights into its biological processes. katana microtome enables the acquisition of the 3D architecture of M.lignano at nanometre resolution, allowing the reconstruction of some cell structures such as cillia, rhabdites, ultrarhabdites and internal vesicles. One significant application was to visualise the intricate network of stem cells in M. lignano, crucial for understanding their remarkable regenerative abilities. This has also helped reveal the unique structural features of the reproductive organs and the interaction of these organs with the surrounding tissues.

Tobacco Seedlings

Tobacco (Nicotiana tabacum) seedlings offer a crucial stage for studying plant development and responses to environmental conditions. Understanding the cellular and subcellular events during seedling development can have significant implications for crop management and genetic engineering efforts. katana microtome is used to visualise the 3D architecture of cell walls and chloroplasts in tobacco seedlings. These structural details can help understand how cell walls expand during plant growth, and the distribution of chloroplasts and their role in seedling development.

Tobacco Seedlings

Tobacco (Nicotiana tabacum) seedlings offer a crucial stage for studying plant development and responses to environmental conditions. Understanding the cellular and subcellular events during seedling development can have significant implications for crop management and genetic engineering efforts. katana microtome is used to visualise the 3D architecture of cell walls and chloroplasts in tobacco seedlings. These structural details can help understand how cell walls expand during plant growth, and the distribution of chloroplasts and their role in seedling development.

Dentin Tubule Occlusion

Sensitive teeth, often caused by exposed dentin tubules, can create significant discomfort for individuals. Various sensitive toothpastes on the market aim to alleviate this issue through a process known as dentin tubule occlusion. A detailed study of this process is crucial to optimising the formulation of these toothpastes. Using katana microtome can visualise the penetration of occlusion agents, usually composed of nanoparticles such as hydroxyapatite or strontium acetate, into dentin tubules. These images reveal how these agents interact with the tubules, their deposition patterns, and ultimately, their effectiveness in tubule occlusion. By comparing pre-treatment and post-treatment images, the occlusion efficacy of various toothpaste formulations can be quantitatively assessed.

Dentin Tubule Occlusion

Sensitive teeth, often caused by exposed dentin tubules, can create significant discomfort for individuals. Various sensitive toothpastes on the market aim to alleviate this issue through a process known as dentin tubule occlusion. A detailed study of this process is crucial to optimising the formulation of these toothpastes. Using katana microtome can visualise the penetration of occlusion agents, usually composed of nanoparticles such as hydroxyapatite or strontium acetate, into dentin tubules. These images reveal how these agents interact with the tubules, their deposition patterns, and ultimately, their effectiveness in tubule occlusion. By comparing pre-treatment and post-treatment images, the occlusion efficacy of various toothpaste formulations can be quantitatively assessed.

Explore Datasets Produced by katana microtome

More SBF-SEM data on WEBKNOSSOS

Imaged on JEOL IT700. Sample courtesy of Dr Isabelle Bonne, National University of Singapore

Imaged on JEOL IT700. Sample courtesy of Dr Isabelle Bonne, National University of Singapore

Imaged on JEOL IT700. Sample courtesy of Dr Isabelle Bonne, National University of Singapore

Imaged on Zeiss Sigma VP. Sample courtesy of Dr Christel Genoud, University of Lausanne

Imaged on Zeiss Sigma VP. Sample courtesy of Dr Christel Genoud, University of Lausanne

Imaged on Zeiss Sigma VP. Sample courtesy of Dr Christel Genoud, University of Lausanne

Imaged on a TESCAN Clara. Sample courtey of Dr Peter Ladurner, University of Innsbruck.

Imaged on a TESCAN Clara. Sample courtey of Dr Peter Ladurner, University of Innsbruck.

Imaged on a TESCAN Clara. Sample courtey of Dr Peter Ladurner, University of Innsbruck.

Imaged on a Zeiss Sigma VP. Sample courtesy of Alan Kuzirian, Marine Biology Laboratory.

Imaged on a Zeiss Sigma VP. Sample courtesy of Alan Kuzirian, Marine Biology Laboratory.

Imaged on a Zeiss Sigma VP. Sample courtesy of Alan Kuzirian, Marine Biology Laboratory.

Imaged on a Zeiss Sigma VP. Sample courtesy of Alan Kuzirian, Marine Biology Laboratory.

Imaged on a Zeiss Sigma VP. Sample courtesy of Alan Kuzirian, Marine Biology Laboratory.

Imaged on a Zeiss Sigma VP. Sample courtesy of Alan Kuzirian, Marine Biology Laboratory.

Imaged on a Hitachi SU7000. Sample courtesy of Dr Ilya Belevich, University of Helsinki

Imaged on a Hitachi SU7000. Sample courtesy of Dr Ilya Belevich, University of Helsinki

Imaged on a Hitachi SU7000. Sample courtesy of Dr Ilya Belevich, University of Helsinki

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Quick answers to your questions.

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Is katana compatible with my SEM?

Why would I use the katana microtome?

How thin can katana microtome cut?

What sample can I study?

What are the optimum working conditions for katana?

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